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Welcome to the 2020 Gates Grubstake Award Program

The Gates Center for Regenerative Medicine and CU Innovations are pleased to announce the Gates Grubstake Fund focused on accelerating basic, clinical, and translational research related to the field of regenerative medicine.

  • Treatments (e.g. biologics, small molecules, gene and cell therapies)
  • Diagnostics, platforms and research tools (e.g. biomaterials, scaffolds, therapeutic targets, cell expansion methods)
  • Devices (e.g. drug delivery, implants, restoration)
  • Cell biology and tissue engineering

Investigators are encouraged to apply if their programs fall within or even adjacent to these fields.

Interested investigators affiliated with the University of Colorado, Children’s Hospital Colorado, and the UCHealth System are encouraged to submit an application. Multiple awards will be granted, the funding limit is $350,000 per award.  

Guidelines

  • Please fill out the application form online
  • Please contact Heather Callahan, Heather.Callahan@cuanschutz.edu with any questions
  • Applications are due by 5 pm Monday, August 24, 2020
  • Investigators whose applications are selected for presentation will be notified in September 2020
  • Presentations to the Investment Committee are planned for November 4th, 2020
  • Awardees are expected to be notified in December 2020

Read more about the Grubstake Awards


Past Winners

Gates Grubstake Fund 2019

  • ​Optimized manufacturing of CD19xCd22 CAR-expressing T cells for the clinic, Terry Fry, M.D.
  • Generation of functional, patient-specific thymi for cell therapy, Holger Russ, Ph.D.
  • Therapeutic peptide for neuroprotection in acute closed-angle glaucoma, Ram Nagaraj, Ph.D.
  • Production of efficacious recombinant hypoglycosylated FSH glycoform, T. Rajendra Kumar, Ph.D.

Gates Grubstake Fund 2018

  • ​Prevention and treatment of pulmonary fibrosis, Ken Liechty, M.D.
  • Heart regeneration by conversion of non-myocytes into functional cardiomyocytes, 
    Kunhua Song, Ph.D.
  • Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells, 
    Mike Verneris, M.D.​

Gates Grubstake Fund 2017

  • Stem Cell-Derived Retinal Transplant to Treat Dry AMD, Maria Valeria Canto-Soler, Ph.D.
  • Clinical Development of Autologous CD117+ Progenitor Cell Therapy for Solid Organ Transplantation, Martin Zamora, M.D.
  • Bioresorbable 3-D Printed Personalized Implant for Cartilage Regeneration in Pediatric Growth Plate Injuries, Karin A. Payne, Ph.D. 

Gates Grubstake Fund 2016

  • Dr. David Wagner: A Novel Therapeutic to Impact Myelin Loss/Regeneration in Multiple Sclerosis 
  • Dr. Kenneth Liechty: Conjugated Nanoceria to Treat Oxidative Stress and Prevent Chronic Inflammation: First Use Treating Diabetic Ulcers
  • Dr. Jeffrey Olson: Intraocular Device to Potentiate Retinal Stem Cell Transplantation in Macular Degeneration 

Gates Grubstake Fund ​​​​2015

  • Ganna Bilousova, Ph.D., and Igor Kogut, Ph.D.: Induced pluripotent stem cell services as a platform for clinical research
  • Steven Dow, DVM, Ph.D., and Mary Ann DeGroote, M.D.: Antimicrobial stem cell therapy for infected diabetic foot ulcers
  • Karin Payne, Ph.D., and Vikas Patel, M.D.: Structural living bone allografts to enhance bone formation in orthopedic surgery

Gates Grubstake Fund 2014

  • Xiao-Jing Wang, M.D., Ph.D.: Human Smad7-based proteins combined with a cell-permeable peptide called Tat.  Tat-Smad7 and its derivatives can be used via topical application to treat at least four diseases: oral mucositis, psoriasis, chronic wounds, and fibrotic diseases.
  • Antonio Jimeno, M.D., Ph.D.: Proprietary humanized mouse model to assess cancer treatments

 

 

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